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Scientists uncover a brand new technique to take a look at for all times on Mars

September 25, 2023
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Scientists uncover a brand new technique to take a look at for all times on Mars
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A new way to test for life on Mars
Schematic illustration of the end-to-end process. (a) ISO-5 clear room upkeep: Earlier than any experimental setup, the working desk, inside wall panels and gear had been sprayed with 70% isopropyl alcohol and Chemgene HLD4L. The area was totally wiped utilizing sterile cleanroom wipes. (b) Graphical illustration of the DNA extraction and evaluation process, from 500 mg of MMS-2 pattern. The obtained DNA will be immediately fed to the nanopore sequencing instrument or, alternatively, be used for DNA mass quantification if the focus is above 10 pg/µl. Credit score: Scientific Reviews (2023). DOI: 10.1038/s41598-023-42170-6

Area scientists have found a brand new course of to check for all times on Mars and on Earth, utilizing cutting-edge expertise to sequence DNA utilizing the tiniest doable pattern of DNA mass.

The researchers from the College of Aberdeen’s Division of Planetary Sciences used a MinION DNA sequencer developed by Oxford Nanopore Applied sciences to detect microorganisms current in tiny quantities of terrestrial soils, and to analyze how they replicate in ambient circumstances.

In consequence, they’ve designed a process that may detect and characterize soil DNA with as little as 2 picogram of DNA mass (the genome of a single cell of a hummingbird has one picogram of DNA).

The invention has vital implications for learning rock and soil samples taken from Martian and terrestrial landscapes to see in the event that they include traces of DNA wanted to assist microbial life.

Ph.D. scholar Jyothi Basapathi Raghavendra produced the analysis beneath the supervision of Professors Javier Martin-Torres and Maria-Paz Zorzano. The analysis has been printed within the journal Scientific Reports.

Professor Martin-Torres mentioned, “There’s a slim likelihood that microbial life exists on Mars as we speak however to search out it we have to function on the pattern scale, and that is the place the scale and energy of the {hardware} that is utilized in area exploration is a vital issue.

“Utilizing the MinION which presents portability with state-of-the-art expertise, we carried out experiments in our clear lab which ensures that testing is not affected by background contamination.

“In doing so we efficiently discovered the bottom DNA detection restrict of the MinION which proves its worth as a robust software for looking for microbial life in samples taken from planetary environments.

“This creates thrilling potentialities for Martian analysis, as the scale and energy of the MinION makes it an excellent candidate for deployment in future exploration missions, utilizing the method we have now developed.

“As well as, it may very well be utilized in inhospitable environments on Earth equivalent to desert or polar areas, in addition to for functions in drugs, pharmacy and chemistry the place organic contamination is undesirable.”

Clive Brown, chief expertise officer of Oxford Nanopore, mentioned, “Area science presents an vital panorama for pushing the capabilities of the Oxford Nanopore platform. This work builds proof for ultra-low inputs, an vital step ahead. Sequencing expertise may very well be tailored for excessive functions equivalent to Mars—and past—offering the instruments wanted to check the extra-terrestrial samples. We goal to push the expertise even additional for when the Mars Pattern Return mission returns in 2033.”

Extra data:
Jyothi Basapathi Raghavendra et al, DNA sequencing on the picogram degree to analyze life on Mars and Earth, Scientific Reviews (2023). DOI: 10.1038/s41598-023-42170-6

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College of Aberdeen


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Scientists uncover a brand new technique to take a look at for all times on Mars (2023, September 25)
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