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Artemis 2 astronauts will double as human experiments on their journey across the moon

September 18, 2025
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Artemis 2 astronauts will double as human experiments on their journey across the moon
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Artemis 2 astronauts can be studied for the way sleep, stress and radiation form human well being in deep area throughout their moon mission subsequent yr.

The second installment of NASA’s Artemis program to return to the moon and set up a sustained human presence in deep area is ready to be the primary crewed flight take a look at of its Orion spacecraft and House Launch System (SLS) rocket. The four-person crew is tasked with placing the vessel by way of its paces within the cislunar setting, and performing a number of science experiments throughout their mission.

A few of that analysis entails the astronauts themselves, who will flip right into a quartet of biomedical topics to assist NASA gather in-flight data on the human body beyond low Earth orbit for the first time in more than 50 years. As they have with hundreds of physiological tests conducted aboard the International Space Station (ISS), NASA will add the research to its growing understanding of the biological repercussions of life in microgravity, according to a recent release.


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Normal measures

One of many experiments the Artemis 2 astronauts will undertake will see them be a part of a long-running NASA effort to construct a complete understanding of how spaceflight impacts human well being. Samples of blood, urine and saliva are being collected within the months earlier than launch, and the astronauts will endure common checks throughout their 10-day mission and follow-ups after their return.

NASA hopes to make use of the samples to trace modifications in cardiovascular well being, vitamin, immunity and stress throughout a number of levels of coaching, flight and restoration.

ARCHeR: Sleep and stress tracking

The Artemis Research for Crew Health and Readiness (ARCHeR) project will investigate how crew performance might be affected by time spent as such a far distance from Earth while inside Orion’s confined space, combined with the astronauts’ demanding schedule.

Each Artemis 2 astronaut will wear wrist sensors to log movement and sleep throughout the mission. Pre- and post-mission evaluations will be compared to in-flight data to better understand how the deep space mission influences the crew’s alertness, stress and ability to work together cohesively.

Breaking space news, the latest updates on rocket launches, skywatching events and more!

Immune system monitoring

Samples provided by the crew before, during and after their mission will also be used to study their immune systems. In this case, immune system markers in their saliva samples will help researchers evaluate how the body reacts to space radiation.

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To save space and power aboard Orion during their mission, the crew is foregoing refrigeration of their in-flight saliva samples, and will instead make their deposits on specially designed dab papers, which will absorb the samples for simpler storage. Once they return, scientists will test the papers for dormant viruses triggered by the microgravity environment — a phenomenon seen aboard the ISS, where stress has been documented as a trigger to reactivate illnesses like chickenpox and shingles.

four astronauts in orange spacesuits pose for a portrait

The crew of NASA’s Artemis 2 mission. From left: mission specialist Christina Koch, pilot Victor Glover, commander Reid Wiseman, and mission specialist Jeremy Hansen. (Image credit: NASA/Josh Valcarcel)

AVATAR organ-on-a-chip study

Artemis 2 astronauts will also be accompanied by thumb-sized “avatars” of themselves, within the type of blood samples grown to simulate bone marrow on organ-on-a-chip units.


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These chips will trip inside Orion because it passes by way of the Van Allen belts — zones of charged particles between the Earth and moon — testing how marrow responds to deep area radiation and microgravity. Outcomes can be in comparison with ISS experiments to see if the chip expertise can precisely predict how tissues react outdoors Earth’s radiation-hardened magnetosphere.

two fingers hold a small transparent pane with intersecting red and blue lines.

An organ chip for conducting bone marrow experiments in area. (Picture credit score: Emulate)

Radiation

Throughout Artemis 1, Orion carried 5,600 passive and 34 active radiation sensors. For Artemis 2, the spacecraft has been reduced to a modest six active sensors inside the cabin. Additionally, astronauts will wear personal dosimeters.

The devices will measure the consistent radiation exposure experienced throughout the mission, and detect sudden spikes from things like solar storms. If readings reach dangerous levels, astronauts can construct a makeshift radiation shield inside Orion, fortifying themselves between the spacecraft’s heatshield and water storage canisters, both of which are better at absorbing penetrating radiation than other onboard materials.

NASA has selected Reid Wiseman, Victor Glover, and Christina Koch, and CSA (Canadian Space Agency) astronaut Jeremy Hansen as the crew for the Artemis 2 mission. They are scheduled to launch no earlier than Feb. 2026, with a launch window that extends through April.



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